Our Publications
Comprehensive split TEV based protein-protein interaction screening reveals TAOK2 as a key modulator of Hippo signalling to limit growth.
2024 | Cellular Signalling
Polygenic risk for schizophrenia converges on alternative polyadenylation as molecular mechanism underlying synaptic impairment
2024 | Preprint (BioRxiV)
Exploiting Cell-Based Assays to Accelerate Drug Development for G Protein-Coupled Receptors.
2024 | International Journal of Molecular Sciences
Profiling of ERBB receptors and downstream pathways reveals selectivity and hidden properties of ERBB4 antagonists.
2024 | iScience
Massively parallel functional dissection of schizophrenia associated noncoding genetic variants.
2023 | Cell
Improved Split TEV GPCR β-arrestin-2 Recruitment Assays via Systematic Analysis of Signal Peptide and β-arrestin Binding Motif Variants Biosensors.
2022 | Biosensors (Basel)
Expression of Lineage Transcription Factors Identifies Differences in Transition States of Induced Human Oligodendrocyte Differentiation
2022 | Cells
Spironolactone alleviates schizophrenia-related reversal learning in Tcf4 transgenic mice subjected to social defeat.
2022 | Schizophrenia
Dissecting intercellular and intracellular signaling networks with barcoded genetic tools.
2021 | Current Opinions in Chemical Biology
PsyCoP – A Platform for Systematic Semi-Automated Behavioral and Cognitive Profiling Reveals Gene and Environment Dependent Impairments of Tcf4 Transgenic Mice Subjected to Social Defeat
2021| Frontiers in Behavioral Neuroscience
Add-on spironolactone as antagonist of the NRG1-ERBB4 signaling pathway for the treatment of schizophrenia: Study design and methodology of a multicenter randomized, placebo-controlled trial.
2020 | Contemporary Clinical Trials Communications
Multiparametric Assays for Accelerating Early Drug Discovery.
2020 | Trends in Pharmacological Science
Monitoring activities of receptor tyrosine kinases using a universal adapter in genetically encoded split TEV assays.
2019 | Cellular and Molecular Life Sciences
Polygenic burden associated to oligodendrocyte precursor cells and radial glia influences the hippocampal volume changes induced by aerobic exercise in schizophrenia patients.
2019 | Translational Psychiatry
Oligodendrocytes as A New Therapeutic Target in Schizophrenia: From Histopathological Findings to Neuron-Oligodendrocyte Interaction.
2019 | Cells
Assessing behavior and cognition in rodents, nonhuman primates, and humans: where are the limits of translation?
2019 | Dialogues in Clinical Neuroscience
Pathway sensor-based functional genomics screening identifies modulators of neuronal activity.
2018 | Scientific Reports
Multiplexed profiling of GPCR activities by combining split TEV assays and EXT-based barcoded readouts
2018 | Scientific Reports
Spironolactone is an antagonist of NRG1-ERBB4 signaling and schizophrenia-relevant endophenotypes in mice
2017 | EMBO Molecular Medicine
Characterizing Dynamic Protein-Protein Interactions Using the Genetically Encoded Split Biosensor Assay Technique Split TEV
2017 | Methods in Molecular Biology
Split protein biosensor assays in molecular pharmacological studies
2016 | Drug Discovery Today
Monitoring G Protein-Coupled Receptor Activation Using the Protein Complementation Technique Split TEV
2015 | Methods in Molecular Biology
Salt-inducible kinases regulate growth through the Hippo signalling pathway in Drosophila
2013 | Nature Cell Biology
Integrated measurement of split TEV and cis-regulatory assays using EXT encoded reporter libraries
2012 | Methods in Molecular Biology
Linking cellular signalling to gene expression using EXT-encoded reporter libraries
2012 | Methods in Molecular Biology
A modification of the split-tobacco etch virus method for monitoring interactions between membrane proteins in mammalian cells
2011 | Analytical Biochemistry
Studying G protein-coupled receptor activation using split-tobacco etch
2011 | Analytical Biochemistry
Activation of Specific Apoptotic Caspases with an Engineered Small-Molecule-Activated Protease
2010 | Cell
Integrated analysis of receptor activation and downstream signaling with EXTassays
2010 | Nature Methods
Kibra is a regulator of the Salvador/Warts/Hippo signaling network
2010 | Developmental Cell
Analysis of transient phosphorylation-dependent protein-protein interactions in living mammalian cells using split-TEV
2008 | BMC Biotechnology
Monitoring regulated protein-protein interactions using split TEV
2006 | Nature Methods